Salivary secretion and oral health in narcolepsy: a pilot study.
Identifieur interne : 000581 ( Main/Exploration ); précédent : 000580; suivant : 000582Salivary secretion and oral health in narcolepsy: a pilot study.
Auteurs : H. Nordgarden [Norvège] ; J L Jensen ; P. Arneberg ; K. StorhaugSource :
- Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [ 0275-1879 ]
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Analyse de régression (MeSH), Candida albicans (isolement et purification), Concentration en ions d'hydrogène (MeSH), Débit sécrétoire (MeSH), Femelle (MeSH), Humains (MeSH), Mâle (MeSH), Narcolepsie (complications), Narcolepsie (physiopathologie), Narcolepsie (traitement médicamenteux), Norvège (MeSH), Projets pilotes (MeSH), Salivation (effets des médicaments et des substances chimiques), Salive (microbiologie), Salive (métabolisme), Santé buccodentaire (MeSH), Statistique non paramétrique (MeSH), Stimulants du système nerveux central (usage thérapeutique), Sujet âgé (MeSH), Xérostomie (étiologie).
- MESH :
- effets des médicaments et des substances chimiques : Salivation.
- isolement et purification : Candida albicans.
- microbiologie : Salive.
- métabolisme : Salive.
- physiopathologie : Narcolepsie.
- traitement médicamenteux : Narcolepsie.
- usage thérapeutique : Narcolepsie, Stimulants du système nerveux central.
- étiologie : Xérostomie.
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de régression, Concentration en ions d'hydrogène, Débit sécrétoire, Femelle, Humains, Mâle, Norvège, Projets pilotes, Santé buccodentaire, Statistique non paramétrique, Sujet âgé.
- Wicri :
- geographic : Norvège.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Candida albicans (isolation & purification), Central Nervous System Stimulants (therapeutic use), Female (MeSH), Humans (MeSH), Hydrogen-Ion Concentration (MeSH), Male (MeSH), Middle Aged (MeSH), Narcolepsy (complications), Narcolepsy (drug therapy), Narcolepsy (physiopathology), Norway (MeSH), Oral Health (MeSH), Pilot Projects (MeSH), Regression Analysis (MeSH), Saliva (metabolism), Saliva (microbiology), Salivation (drug effects), Secretory Rate (MeSH), Statistics, Nonparametric (MeSH), Xerostomia (etiology).
- MESH :
- chemical , therapeutic use : Central Nervous System Stimulants.
- geographic : Norway.
- complications : Narcolepsy.
- drug effects : Salivation.
- drug therapy : Narcolepsy.
- etiology : Xerostomia.
- isolation & purification : Candida albicans.
- metabolism : Saliva.
- microbiology : Saliva.
- physiopathology : Narcolepsy.
- Adolescent, Adult, Aged, Female, Humans, Hydrogen-Ion Concentration, Male, Middle Aged, Oral Health, Pilot Projects, Regression Analysis, Secretory Rate, Statistics, Nonparametric.
Abstract
Complaints of dry mouth and poor dental health are common in persons with narcolepsy. The aim of this study was to investigate whether salivary secretion is reduced in narcolepsy. Persons using tricyclic anti-depressants (TCAs) were excluded, since TCAs are known to reduce salivary secretion. Thus, two patient subgroups were studied, one on central stimulant (CS) treatment (medicated group, n = 12), and one unmedicated group (n = 8), representing all persons with narcolepsy living in the Oslo area meeting these criteria. The survey group and 20 age- and sex-matched healthy control persons without symptoms of dry mouth were examined with respect to the following parameters: unstimulated (UWS) and chewing-stimulated (SWS) whole salivary flow rates, citric-acid-stimulated parotid and submandibular flow rates, buffering effect, and number of some aciduric micro-organisms in the oral cavity. As a group, persons with narcolepsy had lower whole salivary flow rates, a lower buffering effect, and higher Candida albicans scores than the control group. When the patients were divided into the medicated and unmedicated groups, these differences were valid only for the medicated group. Whether the observed differences were effects of CS medication or reflected that these persons were more seriously affected by the disease has to be further explored.
DOI: 10.1111/j.1754-4505.1996.tb00846.x
PubMed: 9084326
Affiliations:
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Le document en format XML
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xml:lang="fr"><term>Norvège</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Complaints of dry mouth and poor dental health are common in persons with narcolepsy. The aim of this study was to investigate whether salivary secretion is reduced in narcolepsy. Persons using tricyclic anti-depressants (TCAs) were excluded, since TCAs are known to reduce salivary secretion. Thus, two patient subgroups were studied, one on central stimulant (CS) treatment (medicated group, n = 12), and one unmedicated group (n = 8), representing all persons with narcolepsy living in the Oslo area meeting these criteria. The survey group and 20 age- and sex-matched healthy control persons without symptoms of dry mouth were examined with respect to the following parameters: unstimulated (UWS) and chewing-stimulated (SWS) whole salivary flow rates, citric-acid-stimulated parotid and submandibular flow rates, buffering effect, and number of some aciduric micro-organisms in the oral cavity. As a group, persons with narcolepsy had lower whole salivary flow rates, a lower buffering effect, and higher Candida albicans scores than the control group. When the patients were divided into the medicated and unmedicated groups, these differences were valid only for the medicated group. Whether the observed differences were effects of CS medication or reflected that these persons were more seriously affected by the disease has to be further explored.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9084326</PMID><DateCompleted><Year>1997</Year><Month>04</Month><Day>08</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>09</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0275-1879</ISSN><JournalIssue CitedMedium="Print"><Volume>16</Volume><Issue>3</Issue><PubDate><MedlineDate>1996 May-Jun</MedlineDate></PubDate></JournalIssue><Title>Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry</Title><ISOAbbreviation>Spec Care Dentist</ISOAbbreviation></Journal><ArticleTitle>Salivary secretion and oral health in narcolepsy: a pilot study.</ArticleTitle><Pagination><MedlinePgn>128-33</MedlinePgn></Pagination><Abstract><AbstractText>Complaints of dry mouth and poor dental health are common in persons with narcolepsy. The aim of this study was to investigate whether salivary secretion is reduced in narcolepsy. Persons using tricyclic anti-depressants (TCAs) were excluded, since TCAs are known to reduce salivary secretion. Thus, two patient subgroups were studied, one on central stimulant (CS) treatment (medicated group, n = 12), and one unmedicated group (n = 8), representing all persons with narcolepsy living in the Oslo area meeting these criteria. The survey group and 20 age- and sex-matched healthy control persons without symptoms of dry mouth were examined with respect to the following parameters: unstimulated (UWS) and chewing-stimulated (SWS) whole salivary flow rates, citric-acid-stimulated parotid and submandibular flow rates, buffering effect, and number of some aciduric micro-organisms in the oral cavity. As a group, persons with narcolepsy had lower whole salivary flow rates, a lower buffering effect, and higher Candida albicans scores than the control group. When the patients were divided into the medicated and unmedicated groups, these differences were valid only for the medicated group. Whether the observed differences were effects of CS medication or reflected that these persons were more seriously affected by the disease has to be further explored.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nordgarden</LastName><ForeName>H</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>TAKO-Centre, Oslo, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jensen</LastName><ForeName>J L</ForeName><Initials>JL</Initials></Author><Author ValidYN="Y"><LastName>Arneberg</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Storhaug</LastName><ForeName>K</ForeName><Initials>K</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Spec Care Dentist</MedlineTA><NlmUniqueID>8103755</NlmUniqueID><ISSNLinking>0275-1879</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000697">Central Nervous System Stimulants</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002176" MajorTopicYN="N">Candida albicans</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000697" MajorTopicYN="N">Central Nervous System Stimulants</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009290" MajorTopicYN="N">Narcolepsy</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009664" MajorTopicYN="N" Type="Geographic">Norway</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009909" MajorTopicYN="N">Oral Health</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010865" MajorTopicYN="N">Pilot Projects</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012044" MajorTopicYN="N">Regression Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012472" MajorTopicYN="N">Salivation</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012636" MajorTopicYN="N">Secretory Rate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014987" MajorTopicYN="N">Xerostomia</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1996</Year><Month>5</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1996</Year><Month>5</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1996</Year><Month>5</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9084326</ArticleId><ArticleId IdType="doi">10.1111/j.1754-4505.1996.tb00846.x</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Norvège</li></country><region><li>Østlandet</li></region><settlement><li>Oslo</li></settlement></list><tree><noCountry><name sortKey="Arneberg, P" sort="Arneberg, P" uniqKey="Arneberg P" first="P" last="Arneberg">P. Arneberg</name><name sortKey="Jensen, J L" sort="Jensen, J L" uniqKey="Jensen J" first="J L" last="Jensen">J L Jensen</name><name sortKey="Storhaug, K" sort="Storhaug, K" uniqKey="Storhaug K" first="K" last="Storhaug">K. Storhaug</name></noCountry><country name="Norvège"><region name="Østlandet"><name sortKey="Nordgarden, H" sort="Nordgarden, H" uniqKey="Nordgarden H" first="H" last="Nordgarden">H. Nordgarden</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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